Toxicity of 2-Mercaptopropionylglycine (MPG) on Mouse Liver
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چکیده
منابع مشابه
Toxicity of 2-mercaptopropionylglycine (MPG) on mouse liver.
Undertaken study deals with any vulnerable changes by the radioprotective drug 2-mer captopropionylglycine, after administering in variable concentration (20, 50, 100, 200 and 500 mg/kg body weight) of the liver of adult mice at 1, 3, 7 and 14 days interval. The lower doses, 20 and 50 mg/kg body-weight of MPG did not affect the liver at all while at higher doses of 100, 200 and 500 mg/kg body-w...
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Chemical protection/Ovarian follicle/Gamma irradiation Adult virgin female Swiss albino mice were irradiated with 2.5, 5 and 10 Gy of gamma radiation in the presence and absence of the drug MPG and changes in the ovarian follicular population were scored at various post irradiation intervals of 3 hours to 14 days. The results indicate that the drug has partially prevented the rapid reduction in...
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*疋 田光史,堀 川正克,森 俊雄:金 沢大学薬学部放射薬品化学教室,金 沢市宝町13-1〒920 The radioprotective action and cytotoxicity of various sulfhydryl compounds ; 2-mercapto propionylglycine (MPG), 2-mercaptopropionylglycine-amide (MPG-amide), 2-mercaptopropionyl phenylalanine (MPPA), 2-mercaptopropionylphenylglycine (MPPG), 3-mercaptopropionylglycine (3-MPG), AET, cysteine and cysteamine were compared in irradiated and unirradi...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 1977
ISSN: 0449-3060,1349-9157
DOI: 10.1269/jrr.18.302